Senior Regulatory Affairs Specialist salary in San Francisco, CA
Based on 35 certified H-1B filings at DOL wage level III in the San Francisco-Oakland-Fremont, CA metro area, FY2025–FY2026. Includes Alameda, South San Francisco, Pleasanton, Fremont, Dublin.
Also listed as: Compliance Specialist
Salary range
| Percentile | Salary |
|---|---|
| 10th | $103,875 |
| 25th | $106,000 |
| 50th (median) | $112,736 |
| 75th | $124,385 |
| 90th | $153,825 |
Salary by year
Median salary
Filings per year
Show as table
| Fiscal year | Median | P25 | P75 | Filings |
|---|---|---|---|---|
| FY2020 | $116,500 | $93,716 | $127,000 | 10 |
| FY2021 | $108,144 | $96,875 | $130,543 | 16 |
| FY2022 | $100,000 | $98,030 | $113,750 | 11 |
| FY2023 | $122,665 | $104,120 | $151,700 | 14 |
| FY2024 | – | – | – | 8 |
| FY2025 | $111,368 | $104,000 | $122,827 | 22 |
| FY2026 | $112,736 | $112,736 | $125,000 | 13 |
Cost of living
San Francisco's median senior Regulatory Affairs Specialist salary of $112,736 is worth about $97,500 at national average prices.
Source: BEA Regional Price Parities, 2024 (U.S. = 100; San Francisco = 115.6).
Compared with all workers here
All Regulatory Affairs Specialists in the San Francisco, CA area earned a median of $118,890 in May 2025 (7,500 employed). The H-1B median here is $112,736, 5% lower.
Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.
Employers filing at this level
| Employer | Median | Filings |
|---|---|---|
| Medtronic | too few | 4 |
| Penumbra | too few | 4 |
| St. Jude Medical, Cardiology Division | too few | 3 |
| Amazon | too few | 2 |
| Via Licensing Alliance | too few | 2 |
Employers with at least 2 filings here. Median shown at 10+ filings.
By experience level
| Wage level | Median | Filings |
|---|---|---|
| Entry-level · Level I | $66,585 | 14 |
| Mid-level · Level II | $95,000 | 37 |
| Senior · Level III | $112,736 | 35 |
| Expert · Level IV | $137,839 | 22 |
Median shown when a level has at least 10 filings.
Minimum H-1B salary by level
| Wage level | Prevailing wage (most common) | Median offered salary | Filings |
|---|---|---|---|
| Entry-level · Level I | $64,438 | $66,585 | 14 |
| Mid-level · Level II | $89,814 | $95,000 | 37 |
| Senior · Level III | $112,736 | $112,736 | 35 |
| Expert · Level IV | $123,469 | $137,839 | 22 |
The prevailing wage is the minimum an employer must pay for this job and area. Amounts vary by county within a metro and by wage source.