Regulatory Affairs Specialist salary in San Francisco, CA
Based on 109 certified H-1B filings in the San Francisco-Oakland-Fremont, CA metro area, FY2025–FY2026. Includes Alameda, South San Francisco, Pleasanton, Fremont, Dublin.
Also listed as: Compliance Specialist
Salary range
| Percentile | Salary |
|---|---|
| 10th | $74,751 |
| 25th | $91,402 |
| 50th (median) | $112,736 |
| 75th | $135,678 |
| 90th | $155,900 |
Salary by year
Median salary
Filings per year
Show as table
| Fiscal year | Median | P25 | P75 | Filings |
|---|---|---|---|---|
| FY2020 | $110,232 | $95,239 | $130,000 | 60 |
| FY2021 | $107,639 | $80,000 | $116,178 | 75 |
| FY2022 | $116,355 | $98,030 | $126,100 | 59 |
| FY2023 | $104,478 | $83,000 | $127,562 | 55 |
| FY2024 | $116,250 | $94,073 | $146,682 | 39 |
| FY2025 | $107,271 | $85,109 | $130,250 | 64 |
| FY2026 | $115,000 | $95,888 | $135,678 | 45 |
Cost of living
San Francisco's median Regulatory Affairs Specialist salary of $112,736 is worth about $97,500 at national average prices.
Source: BEA Regional Price Parities, 2024 (U.S. = 100; San Francisco = 115.6).
Compared with all workers here
All Regulatory Affairs Specialists in the San Francisco, CA area earned a median of $118,890 in May 2025 (7,500 employed). The H-1B median here is $112,736, 5% lower.
Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.
Top employers filing
| Employer | Median | Filings |
|---|---|---|
| Medtronic | too few | 7 |
| St. Jude Medical, Cardiology Division | too few | 7 |
| Abbott Diabetes Care | too few | 6 |
| Genentech | too few | 5 |
| Penumbra | too few | 5 |
| California Public Utilities Commission | too few | 4 |
| too few | 3 | |
| Gilead Sciences | too few | 3 |
| Amazon | too few | 2 |
| Meta | too few | 2 |
Employers with at least 2 filings here. Median shown at 10+ filings.
By experience level
| Wage level | Median | Filings |
|---|---|---|
| Entry-level · Level I | $66,585 | 14 |
| Mid-level · Level II | $95,000 | 37 |
| Senior · Level III | $112,736 | 35 |
| Expert · Level IV | $137,839 | 22 |
Median shown when a level has at least 10 filings.
Minimum H-1B salary by level
| Wage level | Prevailing wage (most common) | Median offered salary | Filings |
|---|---|---|---|
| Entry-level · Level I | $64,438 | $66,585 | 14 |
| Mid-level · Level II | $89,814 | $95,000 | 37 |
| Senior · Level III | $112,736 | $112,736 | 35 |
| Expert · Level IV | $123,469 | $137,839 | 22 |
The prevailing wage is the minimum an employer must pay for this job and area. Amounts vary by county within a metro and by wage source.