Senior Molecular and Cellular Biologist salary in San Francisco, CA

Based on 120 certified H-1B filings at DOL wage level III in the San Francisco-Oakland-Fremont, CA metro area, FY2025–FY2026. Includes South San Francisco, Berkeley, Foster City, Redwood City, Emeryville.

Median salary$143,169
Middle 50%$140.2k–$153.8k
vs. all levels here+25%comparison median $114,400
Filings120FY2025–FY2026 · latest two fiscal years

Salary range

Box: middle 50% of filings. Whiskers: 10th–90th percentile. 99% of filings are between $112,558 and $198,537.
PercentileSalary
10th$139,339
25th$140,160
50th (median)$143,169
75th$153,769
90th$170,250

Salary by year

Median salary

$90k $125k $160k FY2020: median $100,000 (73 filings) FY2021: median $110,099 (73 filings) FY2022: median $114,000 (85 filings) FY2023: median $120,964 (72 filings) FY2024: median $137,280 (81 filings) FY2025: median $142,315 (61 filings) FY2026: median $143,777 (59 filings) FY20 FY21 FY22 FY23 FY24 FY25 FY26

Filings per year

FY2020: 73 filings FY20 FY2021: 73 filings FY21 FY2022: 85 filings FY22 FY2023: 72 filings FY23 FY2024: 81 filings FY24 FY2025: 61 filings FY25 FY2026: 59 filings FY26 85
Shaded: FY2025–FY2026, the years behind the figures above. Median shown for years with at least 10 filings. FY2026 covers Q1–Q3 only.
Show as table
Fiscal yearMedianP25P75Filings
FY2020$100,000$95,888$112,88273
FY2021$110,099$108,202$130,00073
FY2022$114,000$108,000$122,60085
FY2023$120,964$108,225$132,19572
FY2024$137,280$127,150$145,80081
FY2025$142,315$139,339$153,00061
FY2026$143,777$140,213$154,69559

Cost of living

San Francisco's median senior Molecular and Cellular Biologist salary of $143,169 is worth about $123,800 at national average prices.

Source: BEA Regional Price Parities, 2024 (U.S. = 100; San Francisco = 115.6).

Compared with all workers here

All Molecular and Cellular Biologists in the San Francisco, CA area earned a median of $138,160 in May 2025 (4,280 employed). The H-1B median here is $143,169, 4% higher.

Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.

Employers filing at this level

EmployerMedianFilings
Genentech$140,21310
AbbVietoo few6
CZ Biohub SFtoo few6
Calico Life Sciencestoo few5
Mammoth Biosciencestoo few5
Altos Labstoo few4
Gilead Sciencestoo few4
Nateratoo few4
The J. David Gladstone Institutestoo few4
Epicrispr Biotechnologiestoo few3

Employers with at least 2 filings here. Median shown at 10+ filings.

By experience level

Wage levelMedianFilings
Entry-level · Level I $86,000 114
Mid-level · Level II $115,000 183
Senior · Level III $143,169 120
Expert · Level IV $175,000 50

Median shown when a level has at least 10 filings.

Minimum H-1B salary by level

Wage levelPrevailing wage (most common)Median offered salaryFilings
Entry-level · Level I$85,197$86,000114
Mid-level · Level II$112,258$115,000183
Senior · Level III$140,213$143,169120
Expert · Level IV$167,877$175,00050

The prevailing wage is the minimum an employer must pay for this job and area. Amounts vary by county within a metro and by wage source.