Research Manager (Natural Sciences) salary in Denver, CO
Based on 10 certified H-1B filings in the Denver-Aurora-Centennial, CO metro area, FY2025–FY2026. Includes Aurora, Golden, Littleton, Parker.
Also listed as: Clinical Research Coordinator, Clinical Research Manager
Salary range
| Percentile | Salary |
|---|---|
| 10th | $77,771 |
| 25th | $80,038 |
| 50th (median) | $95,711 |
| 75th | $164,958 |
| 90th | $197,889 |
Cost of living
Denver's median Research Manager (Natural Sciences) salary of $95,711 is worth about $90,500 at national average prices.
Source: BEA Regional Price Parities, 2024 (U.S. = 100; Denver = 105.8).
Compared with all workers here
All Natural Sciences Managers in the Denver, CO area earned a median of $141,080 in May 2025 (920 employed). The H-1B median here is $95,711, 32% lower.
Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.
Top employers filing
| Employer | Median | Filings |
|---|---|---|
| University of Colorado Denver | too few | 3 |
| Leprino Foods Company | too few | 2 |
Employers with at least 2 filings here. Median shown at 10+ filings.
By experience level
| Wage level | Median | Filings |
|---|---|---|
| Entry-level · Level I | too few | 2 |
| Mid-level · Level II | – | 0 |
| Senior · Level III | – | 0 |
| Expert · Level IV | – | 0 |
Median shown when a level has at least 10 filings.