Mid-level Medical Scientist salary in San Francisco, CA

Based on 71 certified H-1B filings at DOL wage level II in the San Francisco-Oakland-Fremont, CA metro area, FY2025–FY2026. Includes South San Francisco, Foster City, Berkeley, Alameda, Redwood City.

Also listed as: Research Scientist, Associate Research Scientist

Median salary$130,000
Middle 50%$120.1k–$149k
vs. all levels here+4%comparison median $125,278
Filings71FY2025–FY2026 · latest two fiscal years

Salary range

Box: middle 50% of filings. Whiskers: 10th–90th percentile. 99% of filings are between $95,056 and $196,500.
PercentileSalary
10th$120,078
25th$120,078
50th (median)$130,000
75th$148,950
90th$175,000

Salary by year

Median salary

$80k $120k $160k FY2020: median $94,000 (55 filings) FY2021: median $108,750 (52 filings) FY2022: median $115,000 (44 filings) FY2023: median $118,000 (51 filings) FY2024: median $125,141 (40 filings) FY2025: median $125,280 (41 filings) FY2026: median $143,000 (30 filings) FY20 FY21 FY22 FY23 FY24 FY25 FY26

Filings per year

FY2020: 55 filings FY20 FY2021: 52 filings FY21 FY2022: 44 filings FY22 FY2023: 51 filings FY23 FY2024: 40 filings FY24 FY2025: 41 filings FY25 FY2026: 30 filings FY26 55
Shaded: FY2025–FY2026, the years behind the figures above. Median shown for years with at least 10 filings. FY2026 covers Q1–Q3 only.
Show as table
Fiscal yearMedianP25P75Filings
FY2020$94,000$81,445$102,12555
FY2021$108,750$98,654$117,99952
FY2022$115,000$109,928$125,75044
FY2023$118,000$111,509$135,05151
FY2024$125,141$117,416$139,00040
FY2025$125,280$120,078$141,00041
FY2026$143,000$125,278$158,79530

Cost of living

San Francisco's median mid-level Medical Scientist salary of $130,000 is worth about $112,400 at national average prices.

Source: BEA Regional Price Parities, 2024 (U.S. = 100; San Francisco = 115.6).

Compared with all workers here

All Medical Scientists, Except Epidemiologists in the San Francisco, CA area earned a median of $160,180 in May 2025 (7,310 employed). The H-1B median here is $130,000, 19% lower.

Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.

Employers filing at this level

EmployerMedianFilings
Genentech$130,68617
Gilead Sciences$120,07810
Exelixistoo few4
Northern California Institute for Research and Educationtoo few3
Amgentoo few2
Ardelyxtoo few2
Dren Bio Managementtoo few2
Kite Pharmatoo few2
Retro Biosciencestoo few2
Sciencetoo few2

Employers with at least 2 filings here. Median shown at 10+ filings.

By experience level

Wage levelMedianFilings
Entry-level · Level I $107,973 35
Mid-level · Level II $130,000 71
Senior · Level III $150,000 42
Expert · Level IV $181,300 36

Median shown when a level has at least 10 filings.

Minimum H-1B salary by level

Wage levelPrevailing wage (most common)Median offered salaryFilings
Entry-level · Level I$99,715$107,97335
Mid-level · Level II$125,278$130,00071
Senior · Level III$148,678$150,00042
Expert · Level IV$172,099$181,30036

The prevailing wage is the minimum an employer must pay for this job and area. Amounts vary by county within a metro and by wage source.