Mid-level Chemist salary in San Francisco, CA

Based on 43 certified H-1B filings at DOL wage level II in the San Francisco-Oakland-Fremont, CA metro area, FY2025–FY2026. Includes South San Francisco, Berkeley, Hayward, Foster City, Menlo Park.

Also listed as: Quality Control Chemist, Analytical Chemist

Median salary$110,753
Middle 50%$104.9k–$118.6k
vs. all levels here−11%comparison median $124,630
Filings43FY2025–FY2026 · latest two fiscal years

Salary range

Box: middle 50% of filings. Whiskers: 10th–90th percentile. 99% of filings are between $101,546 and $208,178.
PercentileSalary
10th$101,546
25th$104,915
50th (median)$110,753
75th$118,633
90th$138,160

Salary by year

Median salary

$70k $100k $130k FY2020: median $86,237 (17 filings) FY2021: median $82,277 (24 filings) FY2022: median $84,282 (39 filings) FY2023: median $84,750 (20 filings) FY2024: median $104,915 (18 filings) FY2025: median $115,000 (27 filings) FY2026: median $107,877 (16 filings) FY20 FY21 FY22 FY23 FY24 FY25 FY26

Filings per year

FY2020: 17 filings FY20 FY2021: 24 filings FY21 FY2022: 39 filings FY22 FY2023: 20 filings FY23 FY2024: 18 filings FY24 FY2025: 27 filings FY25 FY2026: 16 filings FY26 39
Shaded: FY2025–FY2026, the years behind the figures above. Median shown for years with at least 10 filings. FY2026 covers Q1–Q3 only.
Show as table
Fiscal yearMedianP25P75Filings
FY2020$86,237$86,237$87,00017
FY2021$82,277$72,212$94,56124
FY2022$84,282$78,146$100,50039
FY2023$84,750$84,282$101,28120
FY2024$104,915$96,448$110,71918
FY2025$115,000$104,915$123,50027
FY2026$107,877$101,546$116,68816

Cost of living

San Francisco's median mid-level Chemist salary of $110,753 is worth about $95,800 at national average prices.

Source: BEA Regional Price Parities, 2024 (U.S. = 100; San Francisco = 115.6).

Compared with all workers here

All Chemists in the San Francisco, CA area earned a median of $127,790 in May 2025 (2,180 employed). The H-1B median here is $110,753, 13% lower.

Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.

Employers filing at this level

EmployerMedianFilings
Allure Labs$115,00011
Gilead Sciencestoo few6
Issam Tina Solutionstoo few4
Amgentoo few2
Frontage Laboratoriestoo few2
Meadowhawk Biolabstoo few2

Employers with at least 2 filings here. Median shown at 10+ filings.

By experience level

Wage levelMedianFilings
Entry-level · Level I $81,635 28
Mid-level · Level II $110,753 43
Senior · Level III $141,500 41
Expert · Level IV $152,984 40

Median shown when a level has at least 10 filings.

Minimum H-1B salary by level

Wage levelPrevailing wage (most common)Median offered salaryFilings
Entry-level · Level I$80,870$81,63528
Mid-level · Level II$104,915$110,75343
Senior · Level III$124,842$141,50041
Expert · Level IV$148,117$152,98440

The prevailing wage is the minimum an employer must pay for this job and area. Amounts vary by county within a metro and by wage source.