Senior Biochemist salary in San Diego, CA

Based on 18 certified H-1B filings at DOL wage level III in the San Diego-Chula Vista-Carlsbad, CA metro area, FY2025–FY2026. Includes La Jolla, Oceanside, Carlsbad, Lo Jolla.

Median salary$122,432
Middle 50%$116.4k–$124.9k
vs. all levels here+49%comparison median $82,100
Filings18FY2025–FY2026 · latest two fiscal years

Salary range

Box: middle 50% of filings. Whiskers: 10th–90th percentile. 99% of filings are between $106,946 and $136,660.
PercentileSalary
10th$116,355
25th$116,355
50th (median)$122,432
75th$124,867
90th$135,000

Salary by year

Median salary

$70k $105k $140k FY2021: median $88,462 (13 filings) FY2022: median $109,158 (15 filings) FY2024: median $128,000 (11 filings) FY2026: median $117,013 (10 filings) FY20 FY21 FY22 FY23 FY24 FY25 FY26

Filings per year

FY2020: 2 filings FY20 FY2021: 13 filings FY21 FY2022: 15 filings FY22 FY2023: 6 filings FY23 FY2024: 11 filings FY24 FY2025: 8 filings FY25 FY2026: 10 filings FY26 15
Shaded: FY2025–FY2026, the years behind the figures above. Median shown for years with at least 10 filings. FY2026 covers Q1–Q3 only.
Show as table
Fiscal yearMedianP25P75Filings
FY2020–––2
FY2021$88,462$83,221$115,00013
FY2022$109,158$94,900$119,46515
FY2023–––6
FY2024$128,000$123,943$135,57211
FY2025–––8
FY2026$117,013$116,355$127,37510

Cost of living

San Diego's median senior Biochemist salary of $122,432 is worth about $109,400 at national average prices.

Source: BEA Regional Price Parities, 2024 (U.S. = 100; San Diego = 111.9).

Compared with all workers here

All Biochemists and Biophysicists in the San Diego, CA area earned a median of $121,740 in May 2025 (710 employed). The H-1B median here is $122,432, 1% higher.

Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.

Employers filing at this level

EmployerMedianFilings
Novartis Institutes for BioMedical Researchtoo few4
Gilead Sciencestoo few3
Neurocrine Biosciencestoo few3

Employers with at least 2 filings here. Median shown at 10+ filings.

By experience level

Wage levelMedianFilings
Entry-level · Level I $75,171 38
Mid-level · Level II $81,149 35
Senior · Level III $122,432 18
Expert · Level IV – 0

Median shown when a level has at least 10 filings.

Minimum H-1B salary by level

Wage levelPrevailing wage (most common)Median offered salaryFilings
Entry-level · Level I$79,019$75,17138
Mid-level · Level II$60,590$81,14935
Senior · Level III$116,355$122,43218

The prevailing wage is the minimum an employer must pay for this job and area. Amounts vary by county within a metro and by wage source.