Senior Biochemist salary in Boston, MA
Based on 88 certified H-1B filings at DOL wage level III in the Boston-Cambridge-Newton, MA-NH metro area, FY2025–FY2026. Includes Cambridge, Waltham, Somerville, Lexington, Framingham.
Salary range
| Percentile | Salary |
|---|---|
| 10th | $96,100 |
| 25th | $125,000 |
| 50th (median) | $128,730 |
| 75th | $140,100 |
| 90th | $149,550 |
Salary by year
Median salary
Filings per year
Show as table
| Fiscal year | Median | P25 | P75 | Filings |
|---|---|---|---|---|
| FY2020 | $110,000 | $105,394 | $118,000 | 31 |
| FY2021 | $110,219 | $105,872 | $122,000 | 77 |
| FY2022 | $119,500 | $110,219 | $130,000 | 68 |
| FY2023 | $134,826 | $134,826 | $150,000 | 33 |
| FY2024 | $126,270 | $118,331 | $139,000 | 59 |
| FY2025 | $128,500 | $126,610 | $140,300 | 46 |
| FY2026 | $128,730 | $122,450 | $140,000 | 42 |
Cost of living
Boston's median senior Biochemist salary of $128,730 is worth about $118,900 at national average prices.
Source: BEA Regional Price Parities, 2024 (U.S. = 100; Boston = 108.3).
Compared with all workers here
All Biochemists and Biophysicists in the Boston, MA area earned a median of $131,550 in May 2025 (13,370 employed). The H-1B median here is $128,730, 2% lower.
Source: U.S. Bureau of Labor Statistics, OEWS metropolitan area estimates. BLS wages include some incentive pay; H-1B figures are base salary.
Employers filing at this level
| Employer | Median | Filings |
|---|---|---|
| Biogen | too few | 4 |
| Brigham and Women's Hospital | too few | 4 |
| Entrada Therapeutics | too few | 4 |
| ModernaTX | too few | 4 |
| Takeda Development Center Americas | too few | 4 |
| Tessera Therapeutics | too few | 4 |
| AI Proteins | too few | 3 |
| Amgen | too few | 3 |
| Pfizer | too few | 3 |
| Sanofi US Services | too few | 3 |
Employers with at least 2 filings here. Median shown at 10+ filings.
By experience level
| Wage level | Median | Filings |
|---|---|---|
| Entry-level · Level I | $78,279 | 280 |
| Mid-level · Level II | $107,099 | 210 |
| Senior · Level III | $128,730 | 88 |
| Expert · Level IV | $159,014 | 59 |
Median shown when a level has at least 10 filings.
Minimum H-1B salary by level
| Wage level | Prevailing wage (most common) | Median offered salary | Filings |
|---|---|---|---|
| Entry-level · Level I | $58,469 | $78,279 | 280 |
| Mid-level · Level II | $107,099 | $107,099 | 210 |
| Senior · Level III | $122,450 | $128,730 | 88 |
| Expert · Level IV | $143,894 | $159,014 | 59 |
The prevailing wage is the minimum an employer must pay for this job and area. Amounts vary by county within a metro and by wage source.